Symbol
Name
ID

Sox3
SRY (sex determining region Y)-box 3
MGI:98365

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Panhypopituitarism
Disease(s) Associated with SOX3	Panhypopituitarism
X-linked panhypopituitarism

Mouse Phenotypes

abnormal pituitary gland morphology

abnormal adenohypophysis development

abnormal Rathke's pouch development

bifurcated Rathke's pouch

abnormal pituitary infundibular stalk morphology

absent pituitary infundibular stalk

absent pineal gland

abnormal subcommissural organ morphology

increased atretic ovarian follicle number

abnormal ovarian folliculogenesis

small ovary

abnormal testis morphology

abnormal seminiferous tubule morphology

abnormal Sertoli cell morphology

decreased testis weight

Availability

Mouse Genotype

Sox3^tm1.1Lja/Sox3^tm1.1Lja

Sox3^tm1Rlb/Sox3^tm1Rlb

Sox3^tm1.1Lja/Y

Sox3^tm1Pqt/Y

Sox3^tm1Rlb/Y

Tg(Sox3)1Pqt/0
Tg(Sox3-EGFP)NrPqt/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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